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CPAP provides a pneumatic splint of the upper airway resulting in an increase
in the pharyngeal cross sectional area.
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A full night's polysomnogram demonstrates the optimal CPAP pressure at which
consolidated sleep occurs in all sleep positions and stages of sleep.
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If most apneas and hypopneas are prevented in NREM, and SaO2
stays above 90% in REM withour frequent obstructive breathing events, and an
adequate pressure has been identified.
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There are no definite contraindications to CPAP use, and serious complications
appear to be extremely rare.
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The most common adverse effects are nasal dryness, nasal congestion,
rhinorrhea, and sneezing often treated by humidification.
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Another limiting factor is claustrophobia seen in approximately 2% to 5% of
patients trying CPAP in the laboratory.
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Long-term compliance with CPAP was studied in 121 patients. After 6 months
74.4% were compliant; after 18 months 66.6% reported compliance of symptomatic
benefit and general dislike of the system.
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Compliance of patients followed up at the sleep disorders center (SDC) was: at
6 months 77.8 and at 12 months 72.2, whereas the compliance of patients
followed up by the primary care MD (PMD) was 71.0% at 6 months and 61.3 at 12
months.
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Often, problems that prevent the patient from complying with CPAP can be solved
in regular follow-up visits.